Results 71 to 80 of about 134,426 (309)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The relevance of technology in the organisation of work in a third world workplace: A case study of the Port Harcourt refinery, Nigeria [PDF]
, 1993 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The organisation of work is seen here as concerning the ways in which various elements in work such as skills, tasks and structures of relationship are ...
Nwuche, C.A, Nwuche, Christine Adaobi
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Exploring Service Innovations of Web 2.0 Based on the Viewpoint of Social Construction of Technology [PDF]
, 2010 [[abstract]]With “User-Orientation” as the core value, Web2.0 creates a new culture of user’s initiative participation. Social culture changing drives the development of the network technology. While the related research of Web 2.0 in recent years mainly
Chun-Chin Chung
core
The social construction of facts and artefacts: or How the sociology of science and the sociology of technology might benefit each other [PDF]
, 1984 The need for an integrated social constructivist approach towards the study of science and technology is outlined. Within such a programme both scientific facts and technological artefacts are to be understood as social constructs.
Bijker, Wiebe E. +2 more
core +1 more source
A structural approach of the AI social representations. Robot humanizing technology?
Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής ΕταιρείαςStrongly related to a “technological mythology” referred to Promethean promises and threats, Artificial Intelligence draws increasingly impressive attention from the media, as well as from the lay public.
Patricia Gerakopoulou +1 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Exploring the 'hidden' in organisations: methodological challenges in construction management research [PDF]
, 2009 There has been recognition of the limitations of technocratic approaches to construction management research, and critical theorists in the field have often rejected prescriptive explanations of social phenomena. Thus, there has been a rise in the use of
Chan, Paul, Littlemore, Michelle
core
Redes, 2015 This article proposes the analysis of the concepts of innovation and design of the social aspect in the construction of possible models of social perception, contributing to the building of technological knowledge and changes to environmental rationality.
Rafael Henrique Mainardes Ferreira +3 more
doaj +1 more source