Results 71 to 80 of about 7,469,552 (341)

Mindfulness Meditation Activates Altruism. [PDF]

open access: yes, 2020
Clinical evidence suggests that mindfulness meditation reduces anxiety, depression, and stress, and improves emotion regulation due to modulation of activity in neural substrates linked to the regulation of emotions and social preferences.
Alexander, Marcus   +5 more
core   +1 more source

Humans as Data

open access: yesPress Start, 2021
The fear of humans abusing technology to control others and the sociopolitical order has been at the heart of many dystopian stories. This fear is also at the heart of Watch_Dogs 2, where the centralized city-wide management system made by the Blume ...
Kai Kehrer
doaj  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

« Il te faut mener une vie régulière » : prescriptions et rôle du père durant la grossesse (1960-1962)

open access: yesGenre, Sexualité et Société, 2017
Drawing on a micro-historical study of the correspondence between a couple of primary school teachers in the beginning of the 1960s, this article analyzes the role of fathers during pregnancy.
Fabien Deshayes, Axel Pohn-Weidinger
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Trayectorias contemporáneas del miedo en América Latina

open access: yesLes Cahiers ALHIM, 2017
At the beggining of XXI century, collective fears have dramatically transformed in Latin America. Although this modification is general, it carries specific expressions in each context and Latin America combines a remarkable mixture between changes in ...
David  Barrios Rodríguez
doaj   +1 more source

Reactance to Social Authority in Entertainment-Education Media: Protocol for a Web-Based Randomized Controlled Trial [PDF]

open access: gold, 2021
Alain Vandormael   +6 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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