Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source
Prevenir o crime : o corpo da Polícia Civil de Lisboa
In the implementation of the the law enforcement and punishment of its offenders, the power creates real mechanisms that allow to make these actions effective.
Maria João Vaz
doaj +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Crime and Social Control in Terms of Globalization
Many studies show that regardless of local characteristic in terms of globalization criminal networks are transnational, and local and regional crime are under control of organized crime.
Valentina Zlatanova
doaj
THE SOCIAL BACKGROUND OF VENEREAL DISEASE: A REPORT ON AN EXPERIMENT IN CONTACT TRACING AND AN INVESTIGATION INTO SOCIAL CONDITIONS: TYNESIDE EXPERIMENTAL SCHEME IN VENEREAL DISEASE CONTROL OCTOBER 1943 TO MARCH 1944 [PDF]
openalex +1 more source
PROBLEMS OF CONTROL IN THE SOCIAL SPHERE
The content is more broadly focused on that part of public relations where there is an increasing control deficit. The issue that draws attention and concentrates on itself the analysis is the operation of the administrative control system and its impact on the actions and performance of the executive authority.
Evgeniy Stoyanov+2 more
openaire +8 more sources
Social control and self-control: factors linking exposure to domestic violence and adolescents' Internet gaming addiction. [PDF]
Quancai L, Meng C, Kunjie C.
europepmc +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Defending Others Online: The Influence of Observing Formal and Informal Social Control on One's Willingness to Defend Cyberhate Victims. [PDF]
Costello M+7 more
europepmc +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source