Results 111 to 120 of about 178,898,333 (308)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Report of the National Expert Panel on Social Determinants of Health Equity : recommendations for advancing efforts to achieve health equity [PDF]

open access: yes
Intransigent and growing health inequities call for new thinking about the role of public health in creating the conditions in which all people can be healthy.

core  

Social Determinants of Health: Tenant-Based Housing Voucher Programs

open access: yes
The Community Preventive Services Task Force (CPSTF) findings and recommendations for "Social Determinants of Health: Tenant-Based Housing Voucher Programs" are based on systematic reviews of evidence of effectiveness and economic impact.

core   +1 more source

Self Stigma Among People with Bipolar-I Disorder in Iran

open access: yesIranian Rehabilitation Journal, 2015
Objectives: Psychiatric stigma refers to systemic and internalized stereotypical negative attitudes against individual with mental illness. This article describes the level of self stigma, stereotype endorsement and perceived discrimination experienced ...
Gita Sadighi   +4 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Self-esteem in students of Guilan University of Medical Sciences [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī, 2016
Introduction: Students  particularly, students of medical sciences  not only experience  problems that other students have  but also they  confront specific problems that are related to their job so that, they are threatened more by losing their ...
F Asgari   +3 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Social Determinants of Health: Full Day Kindergarten Programs

open access: yes
The Community Preventive Services Task Force (CPSTF) findings and recommendations for "Social Determinants of Health: Full Day Kindergarten Programs" are based on systematic reviews of evidence of effectiveness and economic impact. All CPSTF findings and

core   +1 more source

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