Results 121 to 130 of about 1,154,433 (290)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Armaghane Danesh Bimonthly Journal, 2015 Background & aim: Unwanted pregnancy increases maternal and child mortality and increases health centers workload. The purpose of this study was to estimate the additional workload caused by unwanted pregnancies in the province's health system of ...
zebaneh Tabeshfar +3 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Increasing nutritional literacy in teachers: the effect of an educational intervention
Payesh, 2018 Objective (s): Lack of attention to nutrition and having non-healthy nutritional habits, is one of the influencing factors for non-communicable diseases.
Mahnaz Hemati +3 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Psychosocial resources and social health inequalities in France: Exploratory findings from a general population survey [PDF]
We study the psychosocial determinants of health, and their impact on social inequalities in health in France. We use a unique general population survey to assess the respective impact on selfassessed health status of subjective perceptions of social ...
Florence Jusot +2 more
core +3 more sources
Action on the social determinants of health through social enterprise [PDF]
, 2017 Krupa, Terry M. +2 more
core +1 more source
Book Review: Social Justice: The Moral Foundations of Public Health and Health Policy [PDF]
, 2007 This essay is a review of Social Justice: The Moral Foundations of Public Health and Health Policy by Madison Powers & Ruth Faden (2006). In this pathbreaking book, senior bioethicists Powers and Faden confront foundational issues about health and ...
West, Robin
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source