Results 131 to 140 of about 178,898,333 (308)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Social Determinants of Health: Out-of-School-Time Programs
The Community Preventive Services Task Force (CPSTF) findings and recommendations for "Social Determinants of Health: Out-of-School-Time Academic Programs" are based on systematic reviews of evidence of effectiveness and economic impact.
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Armaghane Danesh Bimonthly Journal, 2015 Background & aim: Unwanted pregnancy increases maternal and child mortality and increases health centers workload. The purpose of this study was to estimate the additional workload caused by unwanted pregnancies in the province's health system of ...
zebaneh Tabeshfar +3 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2008 The Commission on Social Determinants of Health was set up by former World Health Organization Director-General J.W. Lee. It was tasked to collect, collate, and synthesize global evidence on the social determinants of health and their impact on health ...
core
Increasing nutritional literacy in teachers: the effect of an educational intervention
Payesh, 2018 Objective (s): Lack of attention to nutrition and having non-healthy nutritional habits, is one of the influencing factors for non-communicable diseases.
Mahnaz Hemati +3 more
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source