Results 131 to 140 of about 1,154,433 (290)
Arthritis is the most common disease among the elderly. Identification of factors affecting the prevention of arthritis prevention behaviors for the design of preventive interventions it is very important.
+3 more
doaj
Public health and dental caries in young children in deprived communities in Scotland [PDF]
Dental caries is the most prevalent disease worldwide, and is caused by a complex interaction of tooth susceptibility, nutrition and the oral environment. In young children it can have a major impact on their quality of life, and is the
Chambers, Stephanie
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Impact of health care system on socioeconomic inequalities in doctor use [PDF]
This study examines the impact of health system characteristics on social inequities in health care use in Europe, using data from national surveys in 13 European countries.
Engin Yilmaz, Florence Jusot, Zeynep Or
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Social determinants of health: Closing the gap in primary health care [PDF]
Australian primary health care has a major role to play in addressing social determinants of health (SDOH). This RESEARCH ROUNDup examines the relevance of the Closing the gap in a generation report of the World Health Organization's Commission on Social
Raven, Melissa
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Background &Objective: Global changes have created new health challenges specifically in hospitals. In the new perspective, nowadays hospitals are the best places for health promotion and preventive services.
Shaghayegh Yousefi +3 more
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