Results 131 to 140 of about 1,151,198 (342)

Public health and dental caries in young children in deprived communities in Scotland [PDF]

open access: yes, 2012
Dental  caries  is  the  most  prevalent  disease  worldwide,  and  is  caused  by  a  complex  interaction of tooth susceptibility, nutrition and the oral environment.  In young children it  can have a major impact on their quality of life, and is the 
Chambers, Stephanie
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Self-esteem in students of Guilan University of Medical Sciences [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī, 2016
Introduction: Students  particularly, students of medical sciences  not only experience  problems that other students have  but also they  confront specific problems that are related to their job so that, they are threatened more by losing their ...
F Asgari   +3 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Estimation of the workload added on the health system due to unwanted pregnancies and Children born of these pregnancies in kohgiloyeh Boyrahmad province 2010-2011

open access: yesArmaghane Danesh Bimonthly Journal, 2015
Background & aim: Unwanted pregnancy increases maternal and child mortality and increases health centers workload. The purpose of this study was to estimate the additional workload caused by unwanted pregnancies in the province's health system of ...
zebaneh Tabeshfar   +3 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Increasing nutritional literacy in teachers: the effect of an educational intervention

open access: yesPayesh, 2018
Objective (s): Lack of attention to nutrition and having non-healthy nutritional habits, is one of the influencing factors for non-communicable diseases.
Mahnaz Hemati   +3 more
doaj  

Health Report [PDF]

open access: yes, 2009
This Plan for Health is an unusual undertaking in two respects. It is part of the Go To 2040 regional master plan along with other human services components that have, historically, been outside the purview of planners, who are usually more concerned ...
Amanda LeBreche   +2 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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