Results 101 to 110 of about 13,540,806 (284)

Socioeconomic determinants of rural urban differences in childhood immunisation in India

Discover Social Science and Health
Background In developing countries such as India, vaccine-preventable diseases among infants and women are often associated with malnutrition and poor hygiene conditions. Immunisation plays a crucial role in protecting children from these diseases.
Ankita Sharma, Udai Bhan Singh
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Claimants’ experiences of the social security system during the first wave of COVID-19 [PDF]

, 2021
COVID-19 arrived in the UK early in March 2020. By 23rd March 2020, the UK experienced the first national lockdown. As businesses and livelihoods stalled, an unprecedented number of applications were made for Universal Credit (UC).
Summers, Kate, Summers, K, Ingold, J, Gibbons, Andrea, Gibbons, A, Baumberg Geiger, B, Geiger, Ben Baumberg, de Vries, Robert, Karagiannaki, Eleni, Geiger, BB, Gibbons, AR, Edmiston, D, Baumberg Geiger, Ben, Robertshaw, David, Karagiannaki, E, Ingold, Jo, Scullion, L, Scullion, Lisa, Robertshaw, D, de Vries, R, Scullion, LC, Edmiston, Daniel, Vries, Robert de   +22 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Acquisition of Soft Skills and Affective Outcomes in Online Distance Education: A Secondary School Study

, 2008
Canada is facing a shortage of workers skilled in affective outcomes, specifically soft skills. Some fingers are pointing to the primary and secondary institutions for failing to aptly prepare future employees with those skills.
Hertlein, J. L.
core  

Climate Change and Legal Literacy Consciousness: The Untold Stories from Ghanaian High Schools

Australian Journal of Environmental Education
This study examines the intersection of climate change awareness and legal literacy consciousness among staff and students in Ghanaian senior high schools (SHS) situated in environmentally vulnerable areas. Focusing on district schools within the Central
Stephen Kwabena Asaah-Junior, Felix Oppusu Paapa Agyiri   +1 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Recruitment Questionnaire 2024

Pseudonymized survey microdata from the 2024 Recruitment Questionnaire of The Social Study (TSS) — a probability-based panel survey of individuals aged 16+ residing in private households in Belgium.
The Social Study, TSS
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source