Results 81 to 90 of about 13,540,806 (284)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
LandThe aim of this study is to synthesise the scientific evidence on the implications of urban and rural environments on older adults’ adaptation strategies to heatwaves. Methods: The methodology follows PRISMA guidelines, which involves a systematic search
Pablo De Gea Grela +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Los Angeles County Social Survey, 1993 (LACSS)
, 1993 The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +1 more source
Cogent Business & ManagementPrevious studies on the relationship between innovation orientation and firms’ financial performance have churned out conflicting results. These contradictions motivated this study.
Justice Boateng Dankwah +2 more
doaj +1 more source
Climate Change Impacts and Adaptation to Flow of Swat River and Glaciers in Hindu Kush Ranges, Swat District, Pakistan (2003-2013) [PDF]
International Journal of Economic and Environment Geology, 2016 This work aims at the climate change impacts and adaptation to surface flow of Swat river and glacier resources in Swat river catchments area, Hindu Kush ranges, Northwest Pakistan.
Saifullah Khan, Mahmood-Ul-Hasan
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 1996 This workshop item forms the first of a series of three presented jointly by the University of the West Indies and the International Extension College.
The Distance Education Center of the University of the West Indies and The International Extension College Training Link
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Pakistan Journal of Islamic Research, 2021 Labour market of Muslim world including Pakistan is characterized with lower level of productivity resulting from job dissatisfaction, and undisciplined work environment.
Shahzadah Fahed Qureshi +1 more
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