Results 111 to 120 of about 13,540,806 (284)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Determinants of facilitators’ use of station rotation blended learning: a multigroup moderating effects of facilitators’ discipline, rank and status

open access: yesHumanities & Social Sciences Communications
Station rotation blended learning (SRBL) has emerged as a promising approach in distance education, yet limited empirical evidence exists on lecturers’ acceptance and use of this mode, especially within face-to-face distance learning contexts. This study
Justice Kofi Armah   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Love Lives at a Distance: Distance Relationships over the Lifecourse [PDF]

open access: yes
Distance relationships may be increasingly undertaken by dual-career couples at some point in their life course. Although this can make it difficult to quantitatively measure, the extent of distance relating, qualitative analysis of distance ...
Mary Holmes
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The Social Agenda for Distance Education [PDF]

open access: yes, 2014
Until the turn of the century, the discourse of distance education was essentially about access: trying to reach the underserved populations and the second chance and non-traditional learners and helping developing countries educate large numbers of ...
Bullen, Mark
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Los Angeles County Social Survey, 1996 (LACSS)

open access: yes, 1996
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core   +1 more source

Digital participation outside institutional provision: implications of the access–competence gap for digital transformation in Ghana's basic education system

open access: yesFrontiers in Education
Digital literacy has become a foundational competence for participation in contemporary educational, social, and economic life. However, debates surrounding children's digital engagement often oscillate between concerns about online vulnerability and ...
Hayford Mensah Ayerakwa   +2 more
doaj   +1 more source

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