Results 131 to 140 of about 2,600,869 (337)

Maintaining Politeness in Film Tilik: A Study of Social Distance and Power Relations on Javanese Women [PDF]

open access: diamond, 2021
Fenty Kusumastuti   +2 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Understanding Rural Change: Mobilities, Diversities, and Hybridizations

open access: yesSociální studia, 2016
Rural areas have experienced dramatic changes since the turn of the century, which has made it necessary to theorize their increasing diversity (exurban residential sprawl, international flows of labour, return migrations, neorurals, rural second homes ...
Luis Camarero, Jesús Oliva
doaj  

Neural Similarity and Synchrony among Friends

open access: yesBrain Sciences
Researchers have long recognized that friends tend to exhibit behaviors that are more similar to each other than to those of non-friends. In recent years, the concept of neural similarity or neural synchrony among friends has garnered significant ...
Chao Ma, Yi Liu
doaj   +1 more source

Social Relationships and Trust [PDF]

open access: yes
While social relationships play an important role for individuals to cope with missing market institutions, they also limit individuals' range of trading partners.
Christine Binzel, Dietmar Fehr
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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