Results 71 to 80 of about 2,479,930 (314)

Race, Class, And Gender In Boys\u27 Education: Repositioning Intersectionality Theory [PDF]

open access: yes, 2015
Boys\u27 identities are distinctly gendered, racialized, and classed across disparate social and cultural contexts. Related intersectional identity processes are associated with boys\u27 academic success.
Nelson, Joseph Derrick   +2 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Community perspectives on partnering with early-stage investigators in pilot research

open access: yesResearch Involvement and Engagement
Background This study explores the experiences of community partners who collaborated with early-stage academic investigators on a yearlong NIH-funded health disparities research initiative in Cleveland, Ohio.
Cyleste C. Collins   +4 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The use of social media for improving energy consumption awareness and efficiency: An overview of existing tools [PDF]

open access: yes, 2015
Raising consumers’ awareness of energy consumption is one of the first steps in encouraging the adoption of energy saving behaviours that result in energy efficiency.
Fragidis, G   +4 more
core  

Understanding the Social Experience of Education from Adult Learners in South Australian Rural Communities

open access: yeseTropic: electronic journal of studies in the tropics, 2015
This article offers a preliminary overview of a study that investigates the experiences of adult learners residing in rural communities in the state of South Australia.
Jillian Marchant, Pauline Taylor
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Social skills, executive functioning and social engagement

open access: yesSchizophrenia Research: Cognition, 2019
The study explored hypothesized mediation of social interaction skills between executive functions and social engagement among adolescents diagnosed with schizophrenia. Participants (N = 92; 62% boys; age = 16.8) were assessed four weeks after hospitalization using previously validated scales.
Nir Madjar   +4 more
openaire   +3 more sources

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