Results 81 to 90 of about 655,003 (315)
Community perspectives on partnering with early-stage investigators in pilot research
Research Involvement and EngagementBackground This study explores the experiences of community partners who collaborated with early-stage academic investigators on a yearlong NIH-funded health disparities research initiative in Cleveland, Ohio.
Cyleste C. Collins +4 more
doaj +1 more source
Why people attend science festivals : interests, motivations and self-reported benefits of public engagement with research [PDF]
, 2014 As a form of public engagement, science festivals have rapidly expanded in size and number over recent years. However, as with other domains of informal public engagement that are not linked to policy outcomes, existing research does not fully address ...
Buckley, Nicola, Jensen, Eric
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
eTropic: electronic journal of studies in the tropics, 2015 This article offers a preliminary overview of a study that investigates the experiences of adult learners residing in rural communities in the state of South Australia.
Jillian Marchant, Pauline Taylor
doaj +1 more source
Supporting Asian-American Civic Engagement: Theory and Practice
, 2009 · This paper is a review of relevant research related to the civic engagement of Asian-American youth. · Little work has been done to understand the civic engagement activities of Asian-American youth.
Yi Chan, Wing, Wing Yi Chan
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The challenges of "upstream" communication and public engagement for Irish nanotechnology [PDF]
, 2009 This paper sets out some challenges for Ireland’s contribution to nanotechnology public engagement in the context of current STS and science communication theoretical practice approaches.
Murphy, Padraig
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Social activism: Engaging millennials in social causes
First Monday, 2018 Given that young adults consume and interact with digital technologies not only a daily basis, but extensively throughout the day, it stands to reason they are more actively involved in advocating social change particularly through social media. However, national surveys of civic engagement indicate civic and community engagement drops-off after high ...
openaire +1 more source