Results 51 to 60 of about 2,209,260 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Social Engineering—The Hidden Control

open access: yesProceedings, 2020
The former energy-wasting lifestyles of developed societies can no longer be sustained. In our age, efficiency is the key to continued sustainability. Increasing efficiency requires the use of infocommunication systems and their regulation.
Edina Albininé Budavári   +1 more
doaj   +1 more source

Employer and student perspectives on skills for engineers in the twenty first century and beyond [PDF]

open access: yes, 2010
This research focused on skills identified among final year engineering students. It provided evidence of different levels of skills by students and identifies their greatest learning influences in these areas.
Brabazon, Dermot   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A New Role for Human Resource Managers: Social Engineering Defense [PDF]

open access: yes, 2016
[Excerpt] The general risk of social engineering attacks to organizations has increased with the rise of digital computing and communications, while for an attacker the risk has decreased.
Seidenberger, Scott
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Development of Game-Based Learning Scenarios for Social Engineering and Security Risk Management for SMEs in the Manufacturing Industry [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2021
With increasing digitization, information security (IS) is becoming an important issue for all employees working in companies and organizations. If the human factor is to be seen as a strength rather than a weakness, appropriate awareness-raising ...
Margit Scholl   +2 more
doaj  

Protection against attacks using social engineering tools and methods

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2023
Objective.  In the modern world, innovative technologies are actively developing, communications are moving into the Internet space. Nevertheless, new technologies turned out to be in demand in the segment of organizations, individuals, cyber fraudsters ...
V. A. Repenko, S. A. Reznichenko
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Antisipasi Dampak Social Engineering pada Bisnis Perbankan [PDF]

open access: yes, 2017
Perkembangan teknologi informasi membuat institusi perbankan mengubah strategi bisnis dengan menempatkan teknologi sebagai unsur utama dalam proses inovasi produk dan jasa. Kecanggihan teknologi yang diterapkan oleh institusi perbankan telah diakui mampu
Junaedi, D. I. (Dani)
core  

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