Results 51 to 60 of about 2,195,820 (278)
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Development of Game-Based Learning Scenarios for Social Engineering and Security Risk Management for SMEs in the Manufacturing Industry [PDF]
Journal of Systemics, Cybernetics and Informatics, 2021 With increasing digitization, information security (IS) is becoming an important issue for all employees working in companies and organizations. If the human factor is to be seen as a strength rather than a weakness, appropriate awareness-raising ...
Margit Scholl +2 more
doaj
Protection against attacks using social engineering tools and methods
Вестник Дагестанского государственного технического университета: Технические науки, 2023 Objective. In the modern world, innovative technologies are actively developing, communications are moving into the Internet space. Nevertheless, new technologies turned out to be in demand in the segment of organizations, individuals, cyber fraudsters ...
V. A. Repenko, S. A. Reznichenko
doaj +1 more source
Employer and student perspectives on skills for engineers in the twenty first century and beyond [PDF]
, 2010 This research focused on skills identified among final year engineering students. It provided evidence of different levels of skills by students and identifies their greatest learning influences in these areas.
Brabazon, Dermot +2 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Pretexting and means to counter it
Вестник Дагестанского государственного технического университета: Технические науки, 2023 Objective. Currently, fraud is one of the most pressing problems in modern society. The number of victims of scammers using social engineering methods is growing day by day. Because fraud is a type of crime that is very difficult to prove. The aim of the
U. A. Mikhaleva
doaj +1 more source
Engineering affect: emotion regulation, the internet, and the techno-social niche [PDF]
, 2019 Philosophical work exploring the relation between cognition and the Internet is now an active area of research. Some adopt an externalist framework, arguing that the Internet should be seen as environmental scaffolding that drives and shapes cognition ...
Krueger, Joel, Osler, Lucy
core
An ontology co-design method for the co-creation of a continuous care ontology [PDF]
, 2014 Ontology engineering methodologies tend to emphasize the role of the knowledge engineer or require a very active role of domain experts. In this paper, a participatory ontology engineering method is described that holds the middle ground between these ...
Ackaert, Ann +9 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source