Results 101 to 110 of about 5,180,562 (321)
THE INFLUENCE OF THE SOCIAL ENVIRONMENT ON SEXUAL MATURATION IN MALE MICE [PDF]
John G. Vandenbergh
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Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
The Social and Cultural Environment [PDF]
AbstractPolicy is not made in a vacuum. Disputes over tobacco control are fought within changing policy environments. This chapter explores key population-level factors that influence a national government’s decision to adopt tobacco control policy measures.
openaire +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain+3 more
wiley +1 more source
Social Capital Capacity as Prediction of Dengue Control [PDF]
The program of elimination of mosquito breeding places is still low since there is no public participation effort in vector control. Social capital is key factor for sustaining any health programs implemented.
Kartono, D. T. (Drajat)+3 more
core
STRESS FACTORS OF THE PRODUCTION ENVIRONMENT IN ACTIVITY OF BANK EMPLOYEES
Article is devoted to studying influence of factors of the social environment on human ecology. On selection of the workers’ bank sphere influence a stress factors of the production environment on psycho- emotional and professional health of employees ...
N I Kachanovetskaya
doaj
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Other: Psychiatric Disorder and the Urban Environment: Report of the Cornell Social Science Center. BERTON H. KAPLAN [PDF]
Mirta T. Mulhare
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source