Results 121 to 130 of about 18,481,063 (389)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Qualitative analysis of academic group and discussion forum on Facebook [PDF]
, 2012 In the present study, data was triangulated and two methods of data analysis were used. Qualitative analysis was undertaken of free-text data from students’ reflective essaysto extract socially-related themes. Heuristic evaluation was conducted by expert
Arendt, Dr Hannah +2 more
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
On Causal Relations between Mental Organizer, Action under Mental Processes, and Social Environment [PDF]
, 2006 The purpose of the research was to study the relationships between mental organizers, action under mental process, and social environment through observation.
Laasonen, Ed.D. Raimo J
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Youth Academic Success:It Starts in the Home [PDF]
, 2020 Academic Success of youth is critical for their future success as well as for the economic and social health of their communities. Using a mixed methods approach (the 2008-2013 “Social Capital and Children’s Development” survey and commentaries of eight ...
Ybarra, Veronica Fay
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Impact of Family Members and Friends Habits on Youths Smoking Behaviour: Consequences for Social Marketing [PDF]
Revista de Management Comparat International, 2011 For implementing more effective social marketing programmes for preventing youth’s smoking more information is needed about the backgrounds of their behaviour and choices.
Anne AIDLA , Maaja VADI
doaj
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The Performance Implications of Fit Among Environment, Strategy, Structure, Control System and Social Performance [PDF]
, 2013 Purpose – The paper examined concept of corporate performance. The paper seeks to examine the impact of corporate social performance on the relationship among business environment, strategy, organization, and control system and corporate performance.
Fauzi, Hasan
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source