Results 61 to 70 of about 504,419 (304)

CHINESE-RUSSIAN PARTNERSHIP AND STRATEGIC COOPERATION

open access: yesСравнительная политика, 2019
For most of the time since the establishment of the Chinese-Russian strategic partnership, diplomatic interaction was the main area of strategic cooperation between the two parties.
Liu Fenghua
doaj   +1 more source

Opinion of society as a basis of international relations — analysis of data of public-opinion polls «how citizens of China cognize the world?» [PDF]

open access: yesЭкономика региона, 2012
International links of China were intensified with the realization of policy of reforms. It becomes relevant to understand, how citizens of China cognize the world.
Pan Daly
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

"Social Europe: Still binding regulations?" [PDF]

open access: yes, 2007
We shall begin the paper with a quick reminder of the different steps of Social Europe to date, with an aim of placing the framework of the now-dominant discourse of the impossibility to adopt constraining legislation in Europe.
Pochet, Philippe.
core  

I’m Still Standing: Transposition and political impact of the Directive on Adequate Minimum Wages in the EU

open access: yesItalian Labour Law e-Journal
More than one year after the deadline for the transposition of the European Minimum Wage Directive into national law, this contribution analyses the impact which the Directive already had on minimum wage setting and collective bargaining at national ...
Torsten Müller
doaj   +1 more source

Participation of Lithuanian Innovative SME’s in the European Union Single Market: Political and Legal Aspects [PDF]

open access: yesRevista de Management Comparat International, 2014
The aim: is to study political and legal aspects of Lithuanian SMEs performance in the EU single market. To achieve this aim three tasks were solved: to highlight the linkage between internationalisation and innovation as well as SMEs’ performance in the
Živilė PAUŽAITE, Jurgita BARYNIENE
doaj  

Moments of the Negative. Two Small Nihilist Episodes from the 1940s [PDF]

open access: yesPhainomena
Evoking Leo Strauss’s 1941 text “German Nihilism” and his forceful claim that nihilism is above all “the rejection of the principles of civilization as such,” my intention is to thematize the possible forms of coexistence that survive and develop despite
Petar Bojanić
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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