Results 41 to 50 of about 13,495,052 (294)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

SOCIAL SUPPORT NETWORKS – THE IMPORTANCE OF SOCIAL NETWORKS FOR DISABLED PEOPLE IN DEALING WITH DIFFICULT SITUATIONS [PDF]

open access: yesStudia Humanistyczne AGH, 2018
The main purpose of the article is to show social support of people with disabilities from a structural perspective. This perspective shows the relationship between the structure of social networks of people with disabilities and the actions they take ...
Dorota Żuchowska-Skiba
doaj   +1 more source

Information Acquisition and Exchange In Social Networks [PDF]

open access: yesThe Economic Journal, 2017
A central feature of social networks is information sharing. The Internet and related computing technologies define the relative costs of private information acquisition and forming links with others. This paper presents an experiment on the effects of changing costs.We find that a decline in relative costs of linking makes private investments more ...
Goyal, Sanjeev   +3 more
openaire   +6 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Big Ideas Exchange Highlights Struggle for Cyber Advantage [video]

open access: yes, 2019
Naval Postgraduate School (NPS) faculty and students researching the cutting-edge of how the U.S. can gain an advantage in cyberspace shared their game-changing research during the latest Big Ideas Exchange (BIX), Nov.

core   +2 more sources

Uang Panggilan: Media Pertukaran Sosial dan Tolong Menolong dalam Masyarakat Gadih Angik

open access: yesIndonesian Journal of Religion and Society, 2021
This study raises the theme of Uang panggilan in the Gadih Angik Community Tradition. Call money is a form of tradition in the form of giving a kind of money to the host who is holding a baralek event.
Zainal Abidin, Hulwati Hulwati
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Should Employers Invest in Employability? Examining Employability as a Mediator in the HRM – Commitment Relationship

open access: yesFrontiers in Psychology, 2019
This study investigates the relationship between perceived investments in Human Resource (HR) practices and workplace commitment, from the perspective of social exchange theory.
Jos Akkermans   +3 more
doaj   +1 more source

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