Results 41 to 50 of about 1,520,531 (279)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reciprocity in information exchange: how social exchange enriches collaborative research partnerships

open access: yesInformation Research: An International Electronic Journal
Introduction. This paper explores the information behaviour of researchers engaging with industry, community and government stakeholders. It examines the interplay between information sharing, seeking, encountering and use, and the role of reciprocity ...
Joann Cattlin, Lisa M. Given
doaj   +1 more source

SOCIAL EXCHANGE THEORY : Telaah Konsep George C. Homans Tentang Teori Pertukaran Sosial

open access: yesLisan Al-Hal: Jurnal Pengembangan Pemikiran dan Kebudayaan, 2015
Homans said that every human behavior has a basic psychological explanation. Homans also likened between social behavior and individual behavior. Social exchange theory is on a micro-level. Homans developed it more specific.
Shokhibul Mighfar
doaj   +1 more source

Consequence of psychological distress on performance achievement: A social exchange theory perspective

open access: yesIntangible Capital, 2023
Purpose: This study aimed to examine and analyze the consequences of psychological distress on performance achievement of managers and employees in Islamic micro-finance institutions in Indonesia.
Mohammad Ziad Anwar   +3 more
doaj   +1 more source

Defining sex and virginity loss [PDF]

open access: yes, 2011
This study has examined definitions of sex and virginity loss and the influence of gender, religiosity, middle school sex education, and the importance of virginity on those definitions. The study also tests the applicability of social exchange theory to
Wright, Matthew R.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

INTEGRATING SOCIAL EXCHANGE THEORY AND ENGAGEMENT THEORY: A HOLISTIC APPROACH TO FRANCHISEE-FRANCHISOR RELATIONSHIPS

open access: yesJournal of Business Management and Accounting
Franchisee–franchisor relationships are critical to the sustainability and success of franchise systems, influencing operational consistency and overall brand perception.
Abdul Razak Yahaya
doaj   +1 more source

Making Bonds of Solidarity from Economic Exchange. A Review Essay

open access: yesSociologica, 2020
This article surveys a field of empirical social research linking economic exchange relations to the generation of interpersonal bonds of solidarity. This issue is particularly interesting for both social sciences and current societies because of the ...
Federico Bianchi
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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