Results 91 to 100 of about 1,835,724 (288)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Social Housing and Social Exclusion 2000-2011 [PDF]
By some definitions, social housing, social housing tenants are necessarily socially excluded. In other terms, in 2000, social housing tenants were at greater risk of being socially excluded than owner occupiers and private renters on measures of income,
Rebecca Tunstall
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The Measurement of Social Exclusion [PDF]
This paper develops an axiomatic approach to the measurement of social exclusion. At the individual level, social exclusion is viewed in terms of deprivation of the person concerned with respect to different functionings in the society.
Conchita D'Ambrosio +1 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Health Technology Assessment, 2012 Objectives: To produce a robust measure of social inclusion [Social and Community Opportunities Profile (SCOPE)] that is multidimensional and captures multiple life domains; incorporates objective and subjective indicators of inclusion; has sound ...
P Huxley +6 more
doaj +1 more source
Aid, peasants and social exclusion [PDF]
Using unique village census data collected in 2003 and 2008 in Senegal, we assess the impact of a major World Bank-funded Community Driven Development (CDD) program on membership and assortative matching in community-based organizations (CBOs).
Jean-Louis Arcand, Natascha Wagner
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A measurement of crime control-based social exclusion [PDF]
, 2016 Comparative criminal justice policy has a strong inclination to confront national crime control systems in accordance to corresponding levels of punitiveness.
García-España, Elisa
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Social Exclusion, Social Isolation and the Distribution of Income [PDF]
Social exclusion can be distinguished from social isolation, defining social isolation as the phenomenon of non-participation (of an individual or group) in a society's mainstream institutions, while reserving 'social exclusion' for the subset of cases ...
Brian Barry
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