Results 101 to 110 of about 12,563,706 (287)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Multidimensional Study of Social Exclusion : Rural-to-Urban Migrants in China Post Reform and Opening-up

open access: yes
This paper critically examines the multidimensional mechanisms of social exclusion faced by rural-to-urban migrants in China since the 1978 Reform and Opening-up process, and shows how the interplay of institutional design, market logic and cultural ...
Yang, Xinxian
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

RaRa: Dwarfism, Marginalisation and Social Exclusion in South-west Nigeria [PDF]

open access: yes
This project aims to investigate the social experiences of individuals with dwarfism, or what is popularly known as RaRa, in South-West Nigeria. The study intends to investigate the ways in which these individuals experience marginalisation and social ...
Abiola, Akinyemi
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The relationship between nostalgia, social exclusion, and empathy

open access: yes, 2011
As a positive, social emotion, nostalgia has the potential to reduce the negative impact of social exclusion on empathy. I ran a series of experiments in order to establish the relationship between nostalgia, social exclusion, and empathy.
Cordaro, Filippo
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Making the connections Final report on transport and social exclusion

open access: yes, 2003
SIGLEAvailable from British Library Document Supply Centre- DSC:m03/18077 / BLDSC - British Library Document Supply CentreGBUnited ...
Great Britain. Social Exclusion Unit (United Kingdom)
core  

An Autoethnographic Study on Social Exclusion in Terms of Whiteliness

open access: yes
This autoethnographic thesis analyzes the hinders for whitely people to fully participate in antiracist activism. The author argues that social exclusion /racism is often recreated in the attempts to be inclusive, as emotional features of white fragility
Haukka, Ilona
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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