Results 111 to 120 of about 1,533,792 (313)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Electronic Repository of Russian Historical Statistics: Website [Beta]
, 2014 The Electronic Repository for Russian Historical Statistics brings together data extracted from various published and unpublished sources in one place.
Tykhonov, Vyacheslav +3 more
core
Socially reconstructing history: the Social History Timestream application
Continuum, 2015 For centuries, print media controlled by powerful gatekeepers have played a dominant part in the recording and construction of history. Digital media open up new opportunities for the social construction of historical narratives that reveal personal and situated viewpoints.
Fawns, Tim +6 more
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Interdisciplinary research of the Neolithic Volga-Kama pottery
Documenta Praehistorica, 2013 In this article, we present a new method of studying Neolithic Volga-Kama pottery, which involves typological and technological analysis and the radiocarbon dating of vessels.
Aleksandr Vybornov, Irina Vasilyeva
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Social history, social change and public history
, 2014 Social historians changed how history is done. They also changed how history is defined, and importantly, who history is about. The recognition of the relationship between power, knowledge, cultural symbolism and social memory resulted in a very ...
Suzanne Eckes-Wahl
core
25 years of the Pere Tarrés Faculty of Social Education and Social Work at Universitat Ramon Llull [PDF]
, 2018 Aquest article relata els fets històrics més significatius dels 25 anys de la Facultat d’Educació Social i Treball Social Pere Tarrés, de la Universitat Ramon Llull.
Marzo Arpón, Teresa
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of Arts, Humanities and Social ScienceIraq is a sensitive and geopolitical region in the Middle East from a civilizational point of view, oil, as the most important source of income for the Iraqi government, which provides more than 90% of the annual budget of the government, and this had a ...
Sayeed Ahmad Khalid Sharifi +1 more
doaj +1 more source