Results 91 to 100 of about 2,906,069 (317)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
A cost-benefit approach to labor market reform [PDF]
Labor reforms in Latin America have been scarce compared with the pace of structural reforms aimed at liberalizing product and capital markets. Some analysts contend that without continued liberalization labor market performance will fail to improve ...
Carmen Pages
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The ‘Societal Turn’. Historicising Future Society
Tijdschrift voor Sociale en Economische Geschiedenis, 2018 As a group of young historians we are strongly convinced that the future of social and economic history will be a collective endeavour that crosses institutional and disciplinary boundaries.
Esther Beeckaert +7 more
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
The Future of Global Economic History. Regional Comparisons to Address Global Questions
Tijdschrift voor Sociale en Economische Geschiedenis, 2018 Economic history deals with the process of economic development across the globe in the long-run. In this essay, I put forth ideas about what economic historians should be doing in the next 10 years in terms of content, methodology and the scale of ...
Pim De Zwart
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Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
A comparative perspective on poverty reduction in Brazil, China and India [PDF]
Brazil, China and India have seen falling poverty in their reform periods, but to varying degrees and for different reasons. History left China with favorable initial conditions for rapid poverty reduction through market-led economic growth; at the ...
Ravallion, Martin
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Tijdschrift voor Sociale en Economische Geschiedenis, 2018 Je kunt onmogelijk voorspellen waar toekomstige generaties historici zich mee bezig zullen houden maar je kunt wel stilstaan bij waarneembare trends in het vakgebied.
Jeroen Touwen
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Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Tijdschrift voor Sociale en Economische Geschiedenis, 2018 This article focuses on the determinants of the economic cost of at-home childbirth in Flanders in the nineteenth century. Literature on the remuneration of medical professionals in the nineteenth century is sparse. Yet the few existing studies show that
Christa Matthys
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