Results 91 to 100 of about 3,093,745 (311)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Participación social para el desarrollo local. El caso del municipio de San Luis, Santiago de Cuba
La investigación Participación social para el desarrollo local. El caso del municipio de San Luis, Santiago de Cuba analiza los factores socioculturales que inciden en la participación social para el desarrollo local de un municipio. Los resultados en el
Farah Maria Muguercia Montes de Oca +1 more
doaj +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The socioeconomic reality of three rural peasant localities in the municipality of Coacoatzintla has provoked the migration of male heads of family with the need to obtain employment in other spaces. The consequence of this phenomenon, among many others,
Claudia Lorena Arellano Olivo
doaj +1 more source
Beyond ethics to morality: Choices and relationships in bicultural research settings [PDF]
Knowledge of ourselves as cultural beings, of the values and beliefs of those with whom we work, and of the history of relations among those in our work settings are essential for community and applied social psychologists.
Furness, Jane Amanda +3 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Se presenta una interpretación y análisis comparativo de las aglomeraciones hoteleras en Acapulco y Boca del Río, abarcando un estudio del desarrollo económico – turístico.
Melissa Andrea Bracamonte Jaraba +2 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Information technologies and gambling: a Durkheimian perspective [PDF]
Gambling has a long history as a social practice, through which bonds can be created and maintained, and as a part of creative and reenacted social habits and celebrations.
Mundy-McPherson, S
core

