Results 101 to 110 of about 129,469 (256)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
History, Education and Social Transformation in Africa [PDF]
, 2017 Africa’s current socio-economic predicament is often solely attributed to political and economic mismanagement. However, such an analysis is far from comprehensive, as it fails to account for the historical, sociological and psychological causes of the ...
M.O.E, NWOBA, MICHAEL, UDOIKAH JOSEPH
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Wooden Boats and Shipping Organizations in the Middle Reaches of the Yangtze River (1700-1850)
Tijdschrift voor Sociale en Economische GeschiedenisBetween 1700 and 1850, there were an estimated 125,000 wooden boats in the middle reaches of the Yangtze River, with a load capacity of more than two million tons.
Yao Chen
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Epistemic Conditions and Social Preferences in Trust Games [PDF]
It is well-known that subjects in bilateral bargaining experiments often exhibit choice behavior suggesting there are strong reciprocators in the population.
Gillies, Anthony S, Rigdon, Mary L
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Addendum on the Living Standards of Toronto Blue Collar Workers in the 1900-1914 Era [PDF]
, 1987 This research note follows a recent article in Histoire sociale- Social History on the living conditions of the working class in Toronto during the years 1900-1914.
Chambers, Edward
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2018 In A Transnational History of the Australian Animal Movement, Gonzalo Villanueva covers the important events that led to the addition of an entirely new issue to the political agenda, transforming the conditions of nonhuman animals into a matter of ...
Leth-Espensen, Marie,, Lund University.
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