Results 91 to 100 of about 639,921 (315)
Why I Killed Canadian History: Conditions for an Anti-Racist History in Canada
, 2000 Anti-racism provides the basis for a richer understanding of the past, an understanding that is potentially more sensitive to the requirements of generally accepted standards of historical criticism than is the nationalist framework that shapes most ...
Stanley, Timothy J.
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Interconectando Saberes, 2019 The socioeconomic reality of three rural peasant localities in the municipality of Coacoatzintla has provoked the migration of male heads of family with the need to obtain employment in other spaces. The consequence of this phenomenon, among many others,
Claudia Lorena Arellano Olivo
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Interconectando Saberes, 2018 Se presenta una interpretación y análisis comparativo de las aglomeraciones hoteleras en Acapulco y Boca del Río, abarcando un estudio del desarrollo económico – turístico.
Melissa Andrea Bracamonte Jaraba +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Diverging and Contested Feminisms in Early Social Work History in Ontario (1900-1950)
, 2015 This study examines early Ontario social work history by documenting the lives of four women who contributed to the history of Ontario social work some of whom have largely been forgotten.
Johnstone, Marjorie Winnifred
core +1 more source
Nordic Journal of Vocational Education and TrainingSwedish vocational education and training programmes have become increasingly aligned with labour market demands and employability, with consequent risks of marginalisation of citizenship education and formation. Four subjects that have traditionally played important roles in this, history, religious education, science, and social studies, are now only
Katarina Kärnebro +4 more
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source