Results 91 to 100 of about 129,469 (256)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Social problems in Toledo, 1935 - 1936
This report of social problems in Toledo, Ohio was published in 1936. The statistics and charts presented represent data from both 1935 and 1936 and include dependency, delinquency, arrests and truancy, homes with only present parent, and health ...
Council of Social Agencies (Toledo, Ohio)
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Pour une histoire de la pêche: le marché de la morue à Marseille au XVIIIe siècle [PDF]
, 1981 This paper attempts to trace the parameters of a social and economic history of the Newfoundland fisheries. It examines the relationship between the total catch off Newfoundland (French and English) and the consumption of cod in Marseilles, one of the ...
Turgeon, Laurier
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Mass violence comes not only from states, but also from people. By analyzing mass violence as social interaction through survivor accounts and other sources, this book presents understudied agents, aims and practices of direct violence and ways of action
Gerlach, Christian
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A brief history of social housing
Social housing was invented to deal with the urbanisation of England in the 19th century and the appalling living conditions that developed in cities. Anne Power gives of a brief history of the rise and demise of social housing, from Right to Buy of the ...
Power, Anne
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2017 Latino American History SeriesMark Weitz presents the social and political conditions that influenced the Sleepy Lagoon Murder TrialsAngelo State ...
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