Results 161 to 170 of about 639,921 (315)

La dynamique sociale du catholicisme québécois au XIXe siècle : éléments pour une réflexion sur les frontières et les conditions historiques de possibilité du « social »

open access: yes, 2002
This article studies the many uses and multiple meanings of the term “social” during the nineteenth century. The author argues that liberalism constructed social relations in such a way as to avoid questioning the tensions present in capitalist societies
Fecteau, Jean-Marie
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Excerpt, Oral History Interview, Toshiko Akiyama

open access: yes, 2008
Excerpt, summary, and index of an oral history interview of Toshiko Akiyama. Conducted by Rosalyn Tonai on July 5, 2008, in Klamath Falls, OR. Transcribed by Elizabeth Smith. Edited by Watsunya Ferreira, Brandon H. Unruhe, and Catie Sakurai.The Tule Lake
Toshiko Akiyama, Rosalyn Tonai
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Recompiling History: Code Heritage as a Site for Recovering Marginalized Computing Histories

open access: yes
This paper argues that source code constitutes a legitimate primary source for historical inquiry, capable of revealing social, cultural, and personal dimensions of computing history invisible through conventional archival materials.
KAUFFMANN WILL, Titaÿna
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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