Results 151 to 160 of about 639,921 (315)
Addendum on the Living Standards of Toronto Blue Collar Workers in the 1900-1914 Era
, 1987 This research note follows a recent article in Histoire sociale- Social History on the living conditions of the working class in Toronto during the years 1900-1914.
Chambers, Edward
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Childhood Speech Impairment and Dementia Risks Among U.S. Older Adults. [PDF]
Int J Lang Commun DisordWang H, Xu S, Pei Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Unveiling the hidden burden: Common mental disorders among women attending antenatal care in selected health facilities of Lusaka, Zambia. [PDF]
PLOS Ment HealthJacobs C +4 more
europepmc +1 more source
(Trans)Forming Gender: Social Change and Transgender Citizenship [PDF]
This paper aims to contribute to recent sociological debates about gendered identity constructions and formations, and gendered citizenship, by exploring gender transformation through an analysis of new femininities and masculinities as they are ...
Sally Hines
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Genetic heterogeneity alleviates behavioral trade-off between exploration and vigilance in <i>Drosophila</i>. [PDF]
iScienceOkuyama T, Sato DX, Takahashi Y.
europepmc +1 more source
Segregation in social networks based on acquaintanceship and trust [PDF]
Using newly collected data from the General Social Survey, we compare levels of segregation by race and along other potential dimensions of social cleavage for ties defined in terms of trust and acquaintanceship. We further estimate the size of the trust
DiPrete, Thomas A. +4 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source