Results 71 to 80 of about 2,906,069 (317)
Industrial Life in a Limiting Landscape: An Environmental Interpretation of Stalinist Social Conditions in the Far North [PDF]
International Review of Social History, 2010 SummaryThis paper offers an environmental history of a group of forced migrants who were sent to work on a Soviet industrial project in the far north during the 1930s. As part of the drive to industrialize the country rapidly, the Soviet state deported thousands of peasants who had been declared class enemies to the previously desolate Khibiny ...
openaire +3 more sources
ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function
FEBS Letters, EarlyView.The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran +6 more
wiley +1 more source
Chinese Taukeh, Labourer, and State Control Case Study of Panglong in Eastern Region of Sumatra (1890-1930) [PDF]
, 2017 Recently the flow of labour from China to Indonesia has fuelled many discussions but is not a new phenomenon. It can be traced back to the eighteenth century and continued until the twentieth century.
Erman, E. (Erwiza)
core +3 more sources
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Activismo, literatura y cambio social en el Caribe hispano: aproximación en tres movimientos [PDF]
, 2018 This essay calls for a reflection on the links between literature, activism, and social change in the Hispanic Caribbean, privileging certain interventions led by women, who have contributed to the defense of better living conditions and a more equitable
María Alejandra Aguilar Dornelles
core +2 more sources
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Information technologies and gambling: a Durkheimian perspective [PDF]
, 2014 Gambling has a long history as a social practice, through which bonds can be created and maintained, and as a part of creative and reenacted social habits and celebrations.
Mundy-McPherson, S
core
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source