Results 101 to 110 of about 737,776 (266)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Complexity and identity reconstruction in second language acquisition Complexidade e reconstrução de identidade na aquisição de segunda língua

open access: yesRevista Brasileira de Linguística Aplicada, 2009
The participation of the individual in different discursive practices contributes to the social formation of identity which is not only constituted, but also, fractalized and emerged via discourse.
Liliane Assis Sade
doaj  

Are we talking the Same Language? Challenging Complexity in Country Brand Models [PDF]

open access: yes, 2014
The purpose of this paper is to review recent research into country brand models and identify the most common and shared dimensions. Based on the literature review, this study establishes a conceptual framework to consider the complex interaction between
Mariutti, F, Tench, R
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Thinking Complexity with Harrison White: Towards Social Emergence via Indexical Language

open access: yesSociologica
Harrison C. White, a founding giant of the relational turn in Sociology, has left us a monumental model of social emergence based on the interplay of three primitives (identity, control, switching) and two principles (self-similarity, dispersion) of ...
Jorge Fontdevila
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Understanding informal institutions: Networks and communities in rural development [PDF]

open access: yes, 2005
A major theme within the literature on rural development is that the particular mix of formal and informal institutions present in any situation is a key determinant of development outcomes.
High, Chris   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Islamic–Iranian Identity from the Perspective of Chaos and Complexity Theory

open access: yesجامعه شناسی کاربردی, 2014
Introduction In today's world having multiple identities, national, local, international, religious, occupational, gender, professional, group, tribal, linguistic and so on is a part of the requirements of social life. This paper seeks to investigate the
Hamdallah Akvani   +1 more
doaj  

Citizenship and the Politics of Civic Driven Change [PDF]

open access: yes, 2012
Nation states are premised on the legitimizing presence of a polity comprised of citizens. The politics of this relationship is central to discourse on how societies evolve.
Alan Fowler, Kees Biekart
core  

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