Results 61 to 70 of about 1,773,613 (292)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Social representations of national identity in culturally diverse societies [PDF]
, 2015 The concept of identity, although quite recent in the social sciences (it was popularized by Erikson in the 1950s; see Gleason, 1983), is one of the few concepts to have been so widely studies and theorized. Psychologists, sociologists, anthropologists,
Andreouli, Eleni, Chryssochoou, Xenia
core
Intersectionality and identity: shared tenets and future research agendas for gender and identity studies [PDF]
, 2014 Purpose – The purpose of this paper is to introduce the Special Issue developed from a joint research seminar of the Gender in Management and Identity Special Interest Groups of the British Academy of Management, entitled “Exploring the Intersectionality
Corlett, Sandra, Mavin, Sharon
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Facebook Project - The Missing Box: The Racial Politics Behind the Facebook Interface [PDF]
, 2008 There is no race, ethnicity or nationality category available the default Facebook profile. This, combined with the fact that Facebook is a visually-driven website, suggests that Facebook serves to inadvertently or covertly perpetuate two racist or ...
Ginger, Jeff
core
Between a rock and a hard place: corporate elites in the context of religion and secularism in Turkey [PDF]
, 2014 Drawing on discourse analyses of 36 in-depth interviews with elite business people from Turkey, the study identifies the networking patterns of new and established business elites in the context of economic liberalization and socioreligious ...
Ali Ergur +9 more
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Why are male students less likely to opt for social science courses? : a theory-driven analysis [PDF]
, 2020 Copyright © 2020 SageIn this article, we discuss the question of why only a few men decide to study social science courses such as social work. While the conceptual base of our analysis includes the theory of planned behaviour and theories centring on ...
Hadjar, Andreas, Haunberger, Sigrid
core +1 more source