Results 101 to 110 of about 7,079,688 (312)
Social Justice Documentary: Designing for Impact [PDF]
, 2011 Explores current methodologies for assessing social issue documentary films by combining strategic design and evaluation of multiplatform outreach and impact, including documentaries' role in network- and field-building.
Barbara Abrash, Jessica Clark
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Scientific ReportsUnderstanding vegetation-climate interactions is essential amid escalating global climate change. This study investigates spatial-temporal and seasonal variations in Land Surface Temperature (LST) and Normalized Difference Vegetation Index (NDVI) across ...
Wissanupong Kliengchuay +10 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Applied SciencesPain is a common condition among older adults and a key factor influencing daily functioning. This cross-sectional study examined how pain presence and distribution (no pain, localized pain [LP], and widespread pain [WP]) are related to limitations in ...
Diana Salas-Gómez +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
BMC Public HealthBackground As the opioid crisis rages, maternal prescription opioid misuse (MPOM) is particularly concerning because it influences both the mother and child’s wellbeing. However, little was known about the trend of MPOM and its county-level risk factors.
Xueyi Xing +2 more
doaj +1 more source
Frontiers in PsychologyAlzheimer’s disease (AD) causes a progressive deterioration in the person’s memory and cognitive function, leading to a greater degree of dependency as the disease progresses. This causes a progressive increase in caregiver overload, leading to physical,
Laura Muñoz-Bermejo +7 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Machine Learning with ApplicationsTraining large language models (LLMs) can be prohibitively expensive. However, the emergence of new Parameter-Efficient Fine-Tuning (PEFT) strategies provides a cost-effective approach to unlocking the potential of LLMs across a variety of natural ...
Pitso Walter Khoboko +2 more
doaj +1 more source