Results 191 to 200 of about 11,769,898 (380)

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Editorial: Sport as a tool for social inclusion, employment, and improved health. [PDF]

Front Sports Act Living, 2023
Corvino C, Moriconi M, Costa CM, D'Angelo C.   +3 more
europepmc   +1 more source

Editorial -Special Issue on Social Inclusion and Visual Impairment [PDF]

, 2006
Graeme Douglas, Christine Corcoran, Nigel Charles   +2 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Public administration in contested societies

Administration, 2016
McMahon Denis
doaj   +1 more source

Learnmaths: A Case Study of the Development of Learning Software to Support Social Inclusion [PDF]

, 2006
M.A. Hersh, L. Stapleton
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Bridging the gap between sports/physical activity and prevention of non-communicable diseases through a human rights based approach

Annals of Global Health, 2016
K. Koutsioumpas
doaj   +1 more source

Unmet expectations: social inclusion and the interaction between social anxiety and ambiguous or positive feedback. [PDF]

Front Psychol, 2023
Thériault R, Dion-Cliche F, Dandeneau S.   +2 more
europepmc   +1 more source

Health and mental health policies in Brazil: social exclusion/inclusion as an intention and action [PDF]

, 2002
Ana Tereza de M. C. da Silva, Sônia Barros, Márcia Aparecida Ferreira de Oliveira   +2 more
openalex