Results 101 to 110 of about 4,509,754 (319)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

The Influence of Social Marketing Campaign on Buying Decision (Survey on Students of Brawijaya University\u27s Perspective About 100% Cinta Indonesia Campaign) [PDF]

open access: yes, 2017
The Ministry of Trade of Republic of Indonesia to increase the citizen\u27s pride of local products within “100% Cinta Indonesia” Campaign. This campaign is aimed to increase the awareness of Indonesian consumers.
Mawardi, M. K. (M), Purba, R. M. (Riska)
core  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Estimating Social Influence Using Latent Space Adjusted Approach in R [PDF]

open access: yesarXiv, 2019
Social influence, sometimes referred to as spillover or contagion, have been extensively studied in various empirical social network research. However, there are various estimation challenges in identifying social influence effects, as they are often entangled with other factors, such as homophily in the selection process, the individual's preference ...
arxiv  

When social influence promotes the wisdom of crowds [PDF]

open access: yesarXiv, 2020
Whether, and under what conditions, groups exhibit "crowd wisdom" has been a major focus of research across the social and computational sciences. Much of this work has focused on the role of social influence in promoting the wisdom of the crowd versus leading the crowd astray, resulting in conflicting conclusions about how the social network structure
arxiv  

Influence of Social Multiliteracy Models on Student's Spatial Thinking Skill on Social Studies [PDF]

open access: yes, 2017
This research is motivated the low of student's spatial thinking skill in solving social problems related to the spatial context, This problem will greatly affect the life of the society such as observations made by BNPB about the flood disaster in ...
Muraida, N. L. (Nurul)   +1 more
core  

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The Social Influence of Science [PDF]

open access: yesNature, 1923
IT is true that progress was made in certain directions during the “millenary period of stagnation,” for example, the improvements in mathematics due to the Arabs. Yet the main fact in the re-birth of science in the sixteenth century is the discovery of the work of the Greeks, especially in geometry, astronomy, and geography.
openaire   +3 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

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