Results 101 to 110 of about 27,680,414 (309)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Measuring the usefulness of social media information for new venture development decision-making [PDF]

open access: yes, 2012
Social media are being adopted by a growing number of entrepreneurs. Yet, the majority of academic research has focused on social media as marketing tools.
Groen, Aard   +4 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Affordance Perceptions under Malleable Information Technology: A Social Cognitive Theory Perspective

open access: yes, 2019
Organizations benefit from malleable IT only if users perceive the affordances that malleable IT provides for their work. However, theoretical explanations and empirical evidence related to affordance perception are scarce.
Dibbern, Jens   +2 more
core   +1 more source

Components of a stock market transparency measurement model: a literature review

open access: yesAccounting and Management Research
Transparency is the principle under which the stock market operates; a transparent organization is more likely to attract investors and thus to manage its costs and generate value.
Otilia Miladys Gil Hoyos   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Information Technology

open access: yes, 2008
application/pdf Cover title. "November 21, 2008." Testimony before the Kansas Legislature, Joint Committee on Information Technology, by Candy Shivley, Deputy Secretary, Kansas Department of Social and Rehabilitation Services.Testimony providing ...
Shively, Candy.
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Introducing the Concept of Social Noise [PDF]

open access: yes, 2020
Social Noise is a term I have coined to describe the influence of personal and relational factors on social media information behavior. Knowing that others in the social network may observe posts, comments, and, likes, a user may interact differently ...
Zimmerman, Tara
core  

Migration Processes in the Republic of Kazakhstan: Regularities, Problems, and Prospects

open access: yesDve Domovini
The study’s relevance lies in the ongoing phenomenon of mass migration, which significantly impacts society, economy, and politics worldwide. The purpose is to consider the features of the current situation in the migration field in Kazakhstan and assess
Gulsara Kappassova   +4 more
doaj   +1 more source

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