Results 111 to 120 of about 27,680,414 (309)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A socio-organizational approach to information systems security management in the context of internet banking [PDF]
, 2004 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis takes a social and organizational point of view for studying information systems security in the context of internet banking.
Koskosas, loannis Vasileios
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
EcosphereUrbanization is a significant pressure affecting wildlife and has the potential to greatly alter behavioral responses in animal communities. A behavioral response that is potentially affected by urbanization is the mobbing of predators by potential avian
Benjamin Ewing +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
RECIIS, 2009 In this article we identify some of Armand Mattelart’s main ideas which offer possible approaches to issues addressed by information science. Special attention is given those of his ideas which are connected with the ideological analysis of informational
Carlos Alberto Ávila Araujo
doaj
RUDN Journal of LawThe development of legal regulation of artificial intelligence (AI) represents an urgent priority for most contemporary states. However, progress remains uneven, with few nations achieving a balance between AI technological advancement and protections ...
Elena V. Alferova, Elena V. Skurko
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Recommendation, collaboration and social search [PDF]
, 2011 This chapter considers the social component of interactive information retrieval: what is the role of other people in searching and browsing? For simplicity we begin by considering situations without computers.
Nichols, David M., Twidale, Michael B.
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