Results 121 to 130 of about 27,680,414 (309)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
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Multicomponent approach reveals differences in affective responses among children and adolescents
Investigating age-related shifts in affective responses to emotionally salient stimuli is key to comprehending emotional development during childhood and adolescence.
Kseniia Konopkina +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Transparency and compliance in the procurement process is vital for the financial sustainability and developmental progress of Kitwe City Council.
Clifford Sikanyiti, Kelvin Chibomba
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
This study was aimed at establishing strategies used by the local community to participate in the monitoring and evaluation of Constituency development fund projects and loan disbursement.
Kasiku Akakulubelwa, Clement Katongo
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Information Phenomena in Multiplayer Game Related Social Media
In this chapter, we examine the way games, particularly online games, exist intertwined with social media. In current-day society, the pervasive presence of social media technologies has given rise to games that use social networking sites, forums and ...
Harviainen, J. Tuomas, +2 more
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Empowering community at Kampung 1001 Malam through website development
In the age of information technology, website development has become a crucial solution in empowering communities, and this article highlights the important role that library and information science students play in this endeavour.
Ragil Tri Atmi +6 more
doaj +1 more source

