Results 51 to 60 of about 13,538,934 (258)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Ad hoc innovation by users of social networks: The case of Twitter [PDF]

, 2011
A study on the social networking platform, \u27Twitter\u27, its operations, its impact on daily life and how users have shaped it. Generic, flexible social media spaces such as Facebook and Twitter constitute an increasingly important element in our
Bruns, Axel, Axel Bruns
core   +1 more source

Social innovation: the process development of knowledge-intensive companies [PDF]

, 2012
The new service development of knowledge-intensive companies in emerging economies is changing from processes with only economic goals to processes that combine economic and social needs.
Sandro Battisti, Battisti, Sandro
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Digital Innovation in Social Care - Industry Engagement Workshop : Report [PDF]

The Digital Innovation in Social Care Industry Engagement Workshop (June 2025) brought together 51 participants from industry, academia, health, and social care sectors to explore priorities and opportunities for digital transformation in Scotland’s ...
Raman, Sneha, Whyte, Anna, Whoriskey, Margaret, French, Tara, Lyons, Abigail   +4 more
core   +1 more source

Short-term acute outcomes by clinical and socioeconomic characteristics in adults with SARS-CoV-2: a population-based cohort study focused on the first two years of the COVID-19 pandemic

Archives of Public Health
Background The COVID-19 pandemic disproportionately affected vulnerable populations in terms of comorbidity and socioeconomic disadvantage, both between and within countries.
Alice Corsaro, Federico Banchelli, Rossella Buttazzi, Enrico Ricchizzi, Carlo Gagliotti, Elisa Fabbri, Elisa Gentilotti, Maurizia Rolli, Evelina Tacconelli, Maria Luisa Moro, Nicola Caranci, Elena Berti   +11 more
doaj   +1 more source

Current status of hypertension management operation mechanisms in Chinese mainland and their impact on prevention and control effects: an analysis on official documents

Zhongguo gonggong weisheng
ObjectiveTo evaluate the current status of hypertension prevention and control management operation mechanisms in Chinese mainland, explore the impact of their improvement on hypertension prevention and control effects, and provide a reference for ...
Huihui HUANGFU, Qinwen YU, Peiwu SHI, Qunhong SHEN, Zhaoyang ZHANG, Zheng CHEN, Chuan PU, Lingzhong XU, Zhi HU, Anning MA, Zhaohui GONG, Tianqiang XU, Panshi WANG, Hua WANG, Chao HAO, Qingyu ZHOU, Mo HAO, Chengyue LI   +17 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The current status, challenges, and strategies for high-quality development of the public health system in China

Zhongguo gonggong weisheng
ObjectiveTo systematically evaluate the current status, strengths, and weaknesses of the high-quality development of China’s public health system, and to propose targeted suggestions for improving the system, providing a basis for promoting the high ...
Huihui HUANGFU, Qingyu ZHOU, Huayi ZHANG, Peiyu FENG, Peiwu SHI, Qunhong SHEN, Zhaoyang ZHANG, Zheng CHEN, Chuan PU, Lingzhong XU, Zhi HU, Anning MA, Zhaohui GONG, Tianqiang XU, Panshi WANG, Hua WANG, Chao HAO, Mo HAO, Chengyue LI   +18 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source