Results 71 to 80 of about 13,538,934 (258)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Social Innovation Europe: Country Summary: Poland. Social Innovation in Poland

open access: yes, 2015
The history of social innovation in country, challenges being addressed by social innovation. the key actors, who is promoting social innovation.
Klimczuk, Andrzej
core   +1 more source

Sustainability-oriented social responsibility and corporate innovation

open access: yesChina Journal of Accounting Research
This paper empirically examines how sustainability-oriented social responsibility influences corporate innovation quantity and radical innovation from the perspectives of environment- and employee-oriented social responsibility.
Li Chang, Qian Yu
doaj   +1 more source

Social innovation concept and implementation in the European Union and in the Republic of Lithuania

open access: yesSocial Welfare: Interdisciplinary Approach, 2018
The aim of the paper is to disclose the importance of social innovation and generalize innovation promotion policy in the European Union, assessing the actual situation in Lithuania.
Skaidrė Žičkienė   +1 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Hållbar skolutveckling som social innovation

open access: yes, 2022
I Sverige är nyanlända elever i gymnasieåldern en särskilt utsatt grupp. De behöver på kort tid lära sig svenska från grunden samtidigt som de ska tillgodogöra sig skolämnena på svenska.
Bani-Shoraka, Helena,, Lim Falk, Maria,
core  

A scoping review of narrative analysis in studies of rural depopulation and land abandonment

open access: yesDiscover Sustainability
Rural depopulation and land abandonment are intensifying globally, with acute impacts in Europe’s marginal and inner regions. Although demographic and land-use change are extensively documented quantitatively, less is known about how local communities ...
Rosanna Salvia   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Innovation in Social Science

open access: yesCentral European Journal of Educational Research
Bibliography of the reviewed book: Márkus, E., Boros, J., & Kozma, T. (2022). Sustainability of innovation.
Jennyfer Paola Casas Trujillo
doaj   +1 more source

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