Results 71 to 80 of about 1,062,305 (293)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
"The Social Capital of Regional Dynamics: A Policy Perspective" [PDF]
This paper deals with social capital as an extra-market externality, and its role for innovations and growth. It analyses the changes of innovation activity over time, from early industrialism to the global knowledge economy, how the relations between ...
Hans Westlund
core
Impact of the Human Genome Project at the Interface between Patent and FDA Laws [PDF]
, 1996 Mr. Cunningham stresses the broad scope of biotechnological innovations. Besides endorsing the need for a new oversight commission to deal with potential social issues, he suggests, for example, that some products should be treated like biologics rather ...
Cunningham, Brian C.
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
TECHNOLOGIES AND IMPLEMENTATION TOOLS OF SOCIAL INNOVATIONS OF INDUSTRIAL ENTERPRISES
Вестник Северо-Кавказского федерального университета, 2022 The article examines the possibility of high technologies using to implement social innovations of industrial enterprises. A description of the basic practical technologies and tools for implementing social innovation of industrial enterprises, the use ...
Svetlana Kalyugina
doaj
How change agents and social capital influence the adoption of innovations among small farmers: Evidence from social networks in rural Bolivia [PDF]
"This paper presents results from a study that identified patterns of social interaction among small farmers in three agricultural subsectors in Bolivia—fish culture, peanut production, and quinoa production—and analyzed how social interaction influences
Halgin, Daniel +2 more
core
Oral health promotion and homelessness:a theory-based approach to understanding processes of implementation and adoption [PDF]
, 2015 Objective: To use the Theory of Diffusion of Innovations as a framework to explore the qualitative data gleaned from a process evaluation of the Smile4life intervention across Scottish National Health Service (NHS) Boards and to inform future oral health
Coles E +9 more
core +4 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Technological discontinuities, outsiders and social capital: a case study from Formula 1 [PDF]
, 2012 Purpose – The purpose of this paper is to examine how and why outsiders, rather than incumbents, are able to take advantage of technological discontinuities.
Smith, DJ
core +1 more source