Results 121 to 130 of about 12,385,748 (245)

Research reports : 82nd Annual Pacific Northwest Insect Management Conference [PDF]

open access: yes
Proceedings of the 82nd Annual Pacific Northwest Insect Management Conference, held January 9-10, 2023 in Portland, Oregon.
Pacific Northwest Insect Management Conference
core   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

Innovative Approach Reveals How Receptors Control G Protein State Equilibria

open access: yesAdvanced Science, EarlyView.
Using conformational specific trFRET biosensors of the Gi protein (depicted at the bottom), the authors show that receptor activation can not only release GDP from the inactive G protein, but can also release GTP from the activated G protein, leading to the reformation of the RG ternary complex.
Alexandre Bouyssou   +12 more
wiley   +1 more source

Research reports : 73rd Annual Pacific Northwest Insect Management Conference

open access: yes
Proceedings of the 73rd Annual Pacific Northwest Insect Management Conference, held January 6-7, 2014 at the Hilton Hotel in Portland ...
Pacific Northwest Insect Management Conference
core  

Bio‐Inspired Gradient Heterogeneous Architectures for Ultrasensitive and Robust Strain Sensors via Programmable Crack Engineering

open access: yesAdvanced Science, EarlyView.
Inspired by the insect campaniform sensillum, a heterogeneous bilayer strain sensor is developed based on a unique impedance mismatch and three‐dimensional structural dynamic percolation strategy. The sensor enables real‐time multi‐joint teleoperation of three joints and the gripper using a six‐degree‐of‐freedom robotic‐arm platform.
Qi Wu   +4 more
wiley   +1 more source

Self‐Healing Pd(II) Cage Metallogels for Iodine Capture in Water and Heterogeneous Photocatalysis

open access: yesAdvanced Science, EarlyView.
Two carbazole‐derived metal‐organic cages hierarchically self‐assemble into supramolecular metallogels that integrate autonomous self‐healing, reversible stimuli responsiveness, high‐capacity aqueous iodine capture, and visible‐light‐driven photocatalytic sulfide oxidation within a single multifunctional platform.
Monotosh Dalapati   +3 more
wiley   +1 more source

Research reports : 56th Annual Pacific Northwest Insect Management Conference

open access: yes
Proceedings of the 56th Annual Pacific Northwest Insect Management Conference, held January 6-7, 1997 at the Imperial Hotel in Portland ...
Pacific Northwest Insect Management Conference
core   +1 more source

Research reports : 67th Annual Pacific Northwest Insect Management Conference [PDF]

open access: yes
Proceedings of the 67th Annual Pacific Northwest Insect Management Conference, held January 7-8, 2008 at the Hilton Hotel in Portland ...
Pacific Northwest Insect Management Conference
core  

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

open access: yesAdvanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu   +12 more
wiley   +1 more source

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