Results 41 to 50 of about 12,603,881 (290)
Social isolation in older adults with type 2 diabetes mellitus—a path analysis
Frontiers in Public HealthBackgroundDue to aging, the use of antidiabetic drugs, and dietary restrictions following a diagnosis of type 2 diabetes mellitus (T2DM), the social interactions of older adults with T2DM are often limited.
Jing Wang +6 more
doaj +1 more source
Social isolation among adolescents and its association with depression symptoms
Middle East Current Psychiatry, 2023 Background Social isolation can be defined as the absence of social interactions, contacts, and relationships with family, friends, and neighbors. According to some studies, social isolation was associated with depressive symptoms.
Danah A. Alsadoun +5 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Scientific ReportsDopamine transporter (DAT) via affecting dopaminergic signaling may modulate behavioral alterations in various stressful conditions. The present research aimed to assess the potential deleterious effects of social isolation on behavioral functions and ...
Negin Marghoob, Batool Ghorbani Yekta
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Advancing loneliness and social isolation as global health challenges: taking three priority actions
Public Health Research & Practice, 2023 Loneliness and social isolation have been identified as critical global health issues in the aftermath of the coronavirus disease 2019 (COVID-19) crisis.
Michelle H Lim +5 more
doaj +1 more source
Poststress social isolation exerts anxiolytic effects by activating the ventral dentate gyrus
Neurobiology of Stress, 2023 After aversive stress, people either choose to return to their previously familiar social environment or tend to adopt temporary social withdrawal to buffer negative emotions.
Huiyang Lei +11 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Understanding social isolation and loneliness
, 2022 Social isolation, the objective characteristics of a situation of a small social network, is frequently mentioned as a major risk factor for loneliness and mental health problems.
de Jong Gierveld, J. +6 more
core +1 more source
The effects of social isolation on well-being and life satisfaction during pandemic
Humanities & Social Sciences Communications, 2021 The SARS-CoV-2 pandemic placed many locations under ‘stay at home” orders and adults simultaneously underwent a form of social isolation that is unprecedented in the modern world.
Ruta Clair +3 more
doaj +1 more source