Results 41 to 50 of about 362,272 (255)

The Heterogeneity of Socially Isolated Older Adults: A Social Isolation Typology

Journal of Gerontological Social Work, 2015
Recent statistics show a growing number of older adults who are living alone and are socially isolated. It is against this background that, in recent years, many interventions have been developed to address social isolation among the elderly. Evaluative studies show that most interventions are hardly effective, though.
openaire   +4 more sources

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

The associations of social isolation with depression and anxiety among adults aged 65 years and older in Ningbo, China

Scientific Reports
Social isolation was associated with emotional problems (depression and anxiety) among older adults, however, little is known in China. Thus, we conducted a cross-sectional study including 6,664 ≥ 65 years older adults in Ningbo, China. We collected data
Lian Li, Kaijie Pan, Jincheng Li, Meiqin Jiang, Yan Gao, Hongying Yang, Guolin Bian   +6 more
doaj   +1 more source

Animal‐Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig, Birgit Burkhardt, Christof M. Kramm, Kira Ostermann, Sarah C. Goretzki, Uta Dirksen, Nico Kurpiers, Michael M. Schündeln   +7 more
wiley   +1 more source

Social isolation induces hyperactivity and exploration in aged female mice.

PLoS ONE, 2021
Prolonged social isolation is associated with poor physical and mental health outcomes, findings observed in both humans, and rodent models of isolation.
D Gregory Sullens, Kayla Gilley, Kendall Jensen, Elisabeth Vichaya, Sara L Dolan, Melanie J Sekeres   +5 more
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Modulation of social valence by insular cortex activity during acute social isolation in mice

Molecular Brain
For social animals, social isolation is a potential threat to survival, and therefore can be considered innately aversive. Long-term social isolation induces a variety of social and affective deficits and has been used as a stress model in animal studies,
Kanae Hiyoshi, Daichi Matsushita, Ayako M. Watabe   +2 more
doaj   +1 more source

Recovery from social isolation requires dopamine in males, but not the autism-related gene nlg3 in either sex

Royal Society Open Science
Social isolation causes profound changes in social behaviour in a variety of species. However, the genetic and molecular mechanisms modulating behavioural responses to social isolation and social recovery remain to be elucidated.
Ryley T. Yost, Andrew M. Scott, Judy M. Kurbaj, Brendan Walshe-Roussel, Reuven Dukas, Anne F. Simon   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The experience of social isolation among community-dwelling older adults: a qualitative study

BMC Geriatrics
Background Social isolation is a major problem for older adults. Increasing evidence suggests that perceived social isolation is linked to adverse physical and mental health outcomes among older adults.
Mengfan He, Shitong Guo, Xiang Sun, Yi Yu, Ling Li, Jinhua Zhang, Shiguang Wang, Shuya Li, Peng Wang, Lin Zhang   +9 more
doaj   +1 more source