Results 61 to 70 of about 362,272 (255)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

URDU-INCREASING TRENDS OF SUICIDE AND ITS PREVENTION IN THE LIGHT OF ISLAMIC TEACHINGS

دی اسکالر
Islam believes that human life is a divine trust of Allah and it is a fundamental religious responsibility to protect it. Modern times have seen increasing suicide tendencies due to economic needs, loneliness, destruction of families, mental illnesses ...
Abdul Salam Tunio, Bashir Ahmed Rind
doaj  

Neighborhood social cohesion and physical disorder in relation to social isolation in older adults: racial and ethnic differences

BMC Public Health
Background Neighborhood factors of social isolation have been understudied, hindering efforts to reduce social isolation at the neighborhood level. This study aims to investigate the longitudinal effects of neighborhood social cohesion and physical ...
Weidi Qin, Emily J. Nicklett, Jiao Yu, Ann W. Nguyen   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

GAMBARAN KEMAMPUAN INTERAKSI SOSIAL PASIEN ISOLASI SOSIAL SETELAH PEMBERIAN SOCIAL SKILLS THERAPY DI RUMAH SAKIT JIWA

Jurnal Ilmiah Kesehatan, 2018
Social isolation is one of the nursing diagnoses that can be established in patients who are symptomatic to withdraw, withdraw from social activities and do not want to interact with others even with nurses.
Sukma Ayu Candra Kirana
doaj   +1 more source

SOCIAL ISOLATION AND RESILIENCE [PDF]

Innovation in Aging, 2018
Duyndam, J., Pruchno, R.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Association Between Ego-Resilience and Social Isolation Among Urban Older People

Gerontology and Geriatric Medicine
Social isolation among older adults affects their physical and mental health. Ego-resilience is associated with flexible adaptation to various environments and acceptable behaviors.
Kazuaki Hashimoto MD, PhD, Takeaki Takeuchi MD, PhD, Kazushige Ihara MD, PhD, Shuichi Obuchi PT, PhD, Hisashi Kawai PhD, Hirohiko Hirano DDS, PhD, Yoshinori Fujiwara MD, PhD, Kim Hunkyung PhD, Yutaka Watanabe DDS, PhD, Masahiro Hashizume MD, PhD   +9 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The association of social isolation and loneliness with sarcopenia among the middle-aged and elderly in China

BMC Psychiatry
Objectives This study examined the relationship of social isolation and loneliness on sarcopenia among Chinese middle-aged and elderly people. Methods Social isolation, loneliness, and sarcopenia were measured at baseline. Follow-up measures of new-onset
Lei Tu, Yiqun Li, Xiao Ren, Minglan Jiang, Longyang Han, Xiaowei Zheng   +5 more
doaj   +1 more source