Results 81 to 90 of about 12,603,881 (290)

Association Between Ego-Resilience and Social Isolation Among Urban Older People

Gerontology and Geriatric Medicine
Social isolation among older adults affects their physical and mental health. Ego-resilience is associated with flexible adaptation to various environments and acceptable behaviors.
Kazuaki Hashimoto MD, PhD, Takeaki Takeuchi MD, PhD, Kazushige Ihara MD, PhD, Shuichi Obuchi PT, PhD, Hisashi Kawai PhD, Hirohiko Hirano DDS, PhD, Yoshinori Fujiwara MD, PhD, Kim Hunkyung PhD, Yutaka Watanabe DDS, PhD, Masahiro Hashizume MD, PhD   +9 more
doaj   +1 more source

SOCIAL ISOLATION AND RESILIENCE [PDF]

Innovation in Aging, 2018
Duyndam, J., Pruchno, R.
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Loneliness, social isolation and social capital of ethnic minority/immigrant older adults : a mixed methods investigation

This thesis explores loneliness and social isolation among ethnic minority/immigrant older adults, investigating how ethnicity/immigration intersects with other important social positions—such as age, gender, and socio-economic status—to shape their ...
Joshi, Mengxing
core   +1 more source

The association of social isolation and loneliness with sarcopenia among the middle-aged and elderly in China

BMC Psychiatry
Objectives This study examined the relationship of social isolation and loneliness on sarcopenia among Chinese middle-aged and elderly people. Methods Social isolation, loneliness, and sarcopenia were measured at baseline. Follow-up measures of new-onset
Lei Tu, Yiqun Li, Xiao Ren, Minglan Jiang, Longyang Han, Xiaowei Zheng   +5 more
doaj   +1 more source

GAMBARAN KEMAMPUAN INTERAKSI SOSIAL PASIEN ISOLASI SOSIAL SETELAH PEMBERIAN SOCIAL SKILLS THERAPY DI RUMAH SAKIT JIWA

Jurnal Ilmiah Kesehatan, 2018
Social isolation is one of the nursing diagnoses that can be established in patients who are symptomatic to withdraw, withdraw from social activities and do not want to interact with others even with nurses.
Sukma Ayu Candra Kirana
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Impact of subjective well-being on physical frailty in middle-aged and elderly Japanese with high social isolation.

PLoS ONE
Social isolation exacerbates physical frailty and is associated with subjective well-being. Even those with high levels of social isolation may have different health statuses depending on the type of isolation and their subjective well-being.
Kai Tanabe, Yuki Sugawara, Eiichi Sakurai, Yoichi Motomura, Yukihiko Okada, Akiko Tsukao, Shinya Kuno   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The Key to Healthy Ageing: A Meta-review of Interventions Addressing Social Isolation and Loneliness in Older Adults [PDF]

openSocial isolation and loneliness have a significant impact on the physical and mental health of older adults, with decreased social interactions having substantial adverse effects on ageing.
CAVALLERI, COSTANZA
core