Results 91 to 100 of about 431,994 (303)

Addressing social isolation in high-rise residential buildings in Kuala Lumpur [PDF]

As the urban population grows, the construction of high-rise buildings has increased, often prioritizing functionality and aesthetics over community interactions.
Mohd Noor, Mohd Zairul, Lee, Nur Irdina, Ma’rof, Aini Azeqa   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Using machine learning to understand social isolation and loneliness in schizophrenia, bipolar disorder, and the community

Schizophrenia
Social disconnection, including objective social isolation and subjective loneliness, is linked to substantial health risks. Yet, little is known about the predictors of social disconnection in individuals with mental illness.
Samuel J. Abplanalp, Michael F. Green, Jonathan K. Wynn, Naomi I. Eisenberger, William P. Horan, Junghee Lee, Amanda McCleery, David J. Miklowitz, L. Felice Reddy, Eric A. Reavis   +9 more
doaj   +1 more source

“I Am Actually Scared of Everyone”: Older Adults’ Experiences of Social Isolation during COVID-19: A Qualitative Systematic Review

COVID
The emergence of the coronavirus COVID-19 in December 2019 in Wuhan, China, affected all facets of people’s lives worldwide. As a result of the severity of the pandemic, governments worldwide adopted several policies and containment measures, such as ...
Oladapo Akinlotan, Aishatu Jalo
doaj   +1 more source

Adolescent social isolation influences cognitive function in adult rats

, 2013
Adolescence is a critical period for neurodevelopment. Evidence from animal studies suggests that isolated rearing can exert negative effects on behavioral and brain development.
Wang, Weiwen, Han, Xiao, Sheo, Shuang, Sheo, Feng   +3 more
core  

Data from: Short-term social isolation: Supplemental Figures

These files are part of a collection containing images and tabular summary data supporting all results reported in Zhao, X., Chae, Y., Smith, D., Chen, V., DeFelipe, D., Sokol, J. W., Sadangi, A., & Tschida, K. (2025). Short-term social isolation acts on
Smith, Destiny, Chae, Yurim, Zhao, Xin, DeFelipe, Dylan, Tschida, Katherine A., Sokol, Joshua W., Sadangi, Archana, Chen, Valerie   +7 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A longitudinal framework to describe the relation between age-related hearing loss and social isolation [PDF]

Many older adults live with some form of hearing loss and have difficulty understanding speech in the presence of background sound. Experiences resulting from such difficulties include increased listening effort and fatigue.
Motala, Aysha, Herrmann, Bjorn, Johnsrude, Ingrid   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Social Isolation and Depression among Elderly from an Indian Urban Slum Population

Journal of the Indian Academy of Geriatrics
Background: The aim of the study was to understand the reported prevalence of subjective, objective social isolation, marginal family, and marginal friendship ties in relation to each other.
Mohan Kumar, Manisha Ruikar, V. L. Surya
doaj   +1 more source