Results 91 to 100 of about 137,270 (302)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Social-life cycle assessment of oil palm plantation smallholders in Bengkulu province, Indonesia. [PDF]

Heliyon, 2023
Mulyasari G, Djarot IN, Sasongko NA, Putra AS.   +3 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Towards a method for poverty reduction potential in social life cycle assessment with application to the cobalt supply chain

Purpose About 8% of the world population lives in extreme poverty. The importance of poverty reduction is acknowledged both in the general sustainability literature and within social life cycle assessment (S-LCA).
Arvidsson, Rickard, Brunke, Julia,, Nordelöf, Anders,, Brunke, Julia, Arvidsson, Rickard,, Nordelöf, Anders   +5 more
core   +1 more source

Socio-economic life cycle assessment of future aircraft systems

, 2020
The development of novel aircraft based on electric propulsion is a key strategy to achieve emission reductions in the aviation sector despite the continuously growing demand for air travel.
Thies, Christian, Pinheiro Melo, Sofia, Barke, Alexander, Cerdas, Felipe, Herrmann, Christoph, Spengler, Thomas Stefan   +5 more
core   +1 more source

Applying social life cycle assessment to evaluate the use phase of mobility services: a case study in Berlin. [PDF]

Int J Life Cycle Assess, 2022
Gompf K, Traverso M, Hetterich J.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

On the scientific justification of the use of working hours, child labour and property rights in social life cycle assessment: Three topical reviews

, 2015
PurposeWorking hours, child labour and property rights have been suggested as topics to assess in social life cycle assessment (SLCA). The purpose of this study is to investigate the scientific justification of the current use of these topics.
Baumann, Henrikke, Arvidsson, Rickard, Hildenbrand, Jutta, Baumann, Henrikke,, Arvidsson, Rickard,, Hildenbrand, Jutta,   +5 more
core   +1 more source

Economic, Environmental, and Social Assessment of Concrete Pavement Life Cycle: A Literature Review [PDF]

مهندسی عمران شریف
Concrete is extensively utilized in road pavement construction, including continuously reinforced, jointed plain, jointed reinforced, precast, and eco-block concrete pavements.
Mohammad saleh Entezari, Rashid Tanzadeh, Fereidoon Moghadas Nejad   +2 more
doaj   +1 more source

Comparative Social Life Cycle Assessment of Two Biomass-to-Electricity Systems. [PDF]

Int J Environ Res Public Health, 2021
Martín-Gamboa M, Quinteiro P, Dias AC, Iribarren D.   +3 more
europepmc   +1 more source