Results 101 to 110 of about 1,015,661 (306)

Economic, Environmental, and Social Assessment of Concrete Pavement Life Cycle: A Literature Review [PDF]

open access: yesمهندسی عمران شریف
Concrete is extensively utilized in road pavement construction, including continuously reinforced, jointed plain, jointed reinforced, precast, and eco-block concrete pavements.
Mohammad saleh Entezari   +2 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Which impacts matter for pavement management decisions? Quantifying social sustainability based on a capability approach

open access: yesTransportation Research Interdisciplinary Perspectives
This study addresses the need to evaluate the social sustainability of pavement management decisions, particularly during the use and maintenance stages.
Jessica Boakye, Egemen Okte
doaj   +1 more source

Comparative Social Life Cycle Assessment of Two Biomass-to-Electricity Systems. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Martín-Gamboa M   +3 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Locating Hotspots for the Social Life Cycle Assessment of Bio-Based Products from Short Rotation Coppice. [PDF]

open access: yesBioenergy Res, 2021
Fürtner D   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Life Cycle Assessment and Model Optimization for Sustainable Energy Cross-Border E-Commerce

open access: yesEAI Endorsed Transactions on Energy Web
INTRODUCTION: In an in-depth study of the application of sustainable energy in cross-border e-commerce, a comprehensive assessment and model optimization of its life cycle are conducted to promote the practical application of sustainable development in ...
Hongli Liu, Ruiling Cui
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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