Results 101 to 110 of about 137,270 (302)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A critical review of criticality methods for a European Life Cycle Sustainability Assessment

open access: yes, 2022
The beginning of the 21st century is marked by the fourth industrial revolution, which could be a great opportunity for a sustainable technological transformation. The key role of these technologies in the development of a more sustainable future implies
Freitas de Alvarenga, Rodrigo   +8 more
core   +1 more source

Which impacts matter for pavement management decisions? Quantifying social sustainability based on a capability approach

open access: yesTransportation Research Interdisciplinary Perspectives
This study addresses the need to evaluate the social sustainability of pavement management decisions, particularly during the use and maintenance stages.
Jessica Boakye, Egemen Okte
doaj   +1 more source

Locating Hotspots for the Social Life Cycle Assessment of Bio-Based Products from Short Rotation Coppice. [PDF]

open access: yesBioenergy Res, 2021
Fürtner D   +4 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

On the introduction of a community resilience framework to Social Life Cycle Assessment [Elektronisk resurs]

open access: yes, 2020
SLCA according to the UNEP/SETAC guidelines attempt to measure the social impacts of a product or policy with human well-being as endpoint indicator. However, the methodological sheets do not provide clear and unambiguous definition of what human well ...
Goffetti, Giulia,, Baumann, Henrikke,
core  

Social Life Cycle Assessment Application: Stakeholder Implication in the Cultural Heritage Sector

open access: yes, 2015
The word “sustainability” is often used to refer to equity within and between generations, as explained in the Brundtland Report (1987). The clarification of the concept in the triple bottom line is often used to illustrate the need to investigate the
GUGLIELMETTI MUGION, ROBERTA   +5 more
core   +1 more source

Life Cycle Assessment and Model Optimization for Sustainable Energy Cross-Border E-Commerce

open access: yesEAI Endorsed Transactions on Energy Web
INTRODUCTION: In an in-depth study of the application of sustainable energy in cross-border e-commerce, a comprehensive assessment and model optimization of its life cycle are conducted to promote the practical application of sustainable development in ...
Hongli Liu, Ruiling Cui
doaj   +1 more source

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