Results 131 to 140 of about 137,270 (302)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Showcasing life cycle management
Industries following a linear approach assume that ‘if they produce more, they will sell more’. As new trends in production and consumption models emerge due to growing social, environmental and economic pressures, the linear approach is being replaced ...
Cano Londoño, Natalia AndreaCA100002212947868020040454410000-0003-4828-6442da2e1992-e388-11ec-a039-aec0cdf8977c +3 more
core
PurposeWhile the environmental and economic aspects of sustainability have been extensively studied, social sustainability has been largely neglected and necessitates a thorough investigation.
Fidan, Fatma Şener +3 more
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
This study applies a Social Life Cycle Assessment (S-LCA) to evaluate the social impacts of Furcellaria lumbricalis red macroalgae production through wild harvesting (WH) and offshore cultivation (OC) in the Baltic Sea Region. As macroalgae gain interest
Paoli Riccardo +3 more
doaj +1 more source
Despite legume-based proteins being more environmentally sustainable compared to conventional meat proteins, these products need to be backed up by socially sustainable supply chains, as upstream and downstream social impacts may hinder their overall ...
Edoardo Desiderio, Karin Östergren
doaj +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Enhanced Assessment of the Air Transportation System
A framework has been developed to conduct sustainability studies of ATS and its sub elements separately. The framework shows the combination of Life Cycle Assessment (LCA), Life Cycle Cost Assessment (LCC) and Social Life Cycle Assessment (SLCA).
Gmelin, Tillmann +2 more
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Intersectionality Between Amazon and Commodities Production: A Close Look at Sustainability
Food production’s environmental, economic, and social challenges should be demystified through quantitative data. Therefore, the objective of this paper was to investigate the ecoregional sustainability of the Amazon biome from the perspective of the ...
Adriane Terezinha Schneider +7 more
doaj +1 more source

