Results 61 to 70 of about 1,015,661 (306)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Continuous improvement planning through sustainability assessment of product-service systems [PDF]
, 2016 The paper presents a methodology for the integrated sustainability assessment of a product-service system lifecycle, with the purpose to support continuous improvement on the side both of the manufacturer and of the user. Its eight steps are an extension
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Equity-centred social life cycle assessment of lithium-ion battery recycling
Future BatteriesThe rapid growth of electric vehicles is accelerating demand for lithium-ion battery recycling, yet most assessments overlook the social equity implications of facility siting and technology choice.
Esther O. Oluwabiyi +5 more
doaj +1 more source
Sustainability Assessment of a Residential Building using a Life Cycle Assessment Approach
Chemical Engineering Transactions, 2019 Building and construction industry is responsible for resource scarcity, global warming impacts, land use changes and the loss of bio-diversity, which have direct and indirect socio-economic implications.
Shahana Y. Janjua +2 more
doaj +1 more source
Social Sustainability in Trade and Development Policy: A Life Cycle Approach to Understanding and Managing Social Risk Attributable to Production and Consumption in the EU-27 [PDF]
, 2013 Improving social sustainability within Europe and abroad is among the founding premises of the European Union. European Commission external policy documents – in particular, those associated with trade and development - explicitly call for the use of ...
BENOIT Catherine +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BuildingsPurpose: This paper conducts a review of the different research carried out recently on the behavior of non-structural elements (NSEs) and the life cycle assessment (LCA) during an earthquake. It focuses on the study conducted recently and identifies the
Zeeshan Ahmad +3 more
doaj +1 more source
LCSA Framework for Assessing Sustainability of Alternative Fuels for Transport Sector
Chemical Engineering Transactions, 2019 Consideration of alternative transport fuels, produced from feedstocks and renewable resources, is inevitable to enhance energy security and alleviate environmental burdens.
Najmul Hoque +3 more
doaj +1 more source