Results 41 to 50 of about 238,297 (301)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Social Media and Consumer Culture: Addicted to the Idealized Consumer [PDF]

open access: yes, 2018
For better or for worse, social media has become party of the fabric of society. As technology and social networking sites increasingly affect the behavior and culture around us, signs of digital addiction are on the rise.
Laeder, James
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Mediating Role of Self-Esteem Between Meaning in Life and Social Media Addiction

open access: yesAddicta: The Turkish Journal on Addictions
The advent of digital technologies has markedly transformed human interactions and communication. While social media platforms facilitate connectivity and information sharing, their compelling features, such as instant notifications and one-click ...
Berhan Akdağ, Cansu Ünsal
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Autonomy, special offers and routines: a Q methodological study of industry-driven marketing influences on young people's drinking behaviour [PDF]

open access: yes, 2014
AIM: To identify shared patterns of views in young people relating to the influence of industry-driven alcohol marketing (price, promotion, product and place of purchase/consumption) on their reported drinking behaviour.
Akhtar-Danesh   +50 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Dark triad and social media addiction: A meta-analysis

open access: yesKlinik Psikoloji Dergisi
The dark triad consists of three personality traits including narcissism, Machiavellianism, and psychopathy. Social media addiction is defined as individuals’ losing control over social media use and thus experiencing negative reflections on academic ...
Bilal Kaya
doaj   +1 more source

The relationship between social media addiction and depression: a quantitative study among university students in Khost, Afghanistan

open access: yesInternational Journal of Adolescence and Youth, 2020
This study examined the relationship between social media addiction and depression among students of the universities in Khost province of Afghanistan. Stratified random sampling was used and a 46-items self-administered questionnaire was distributed to ...
Rahmatullah Haand, Zhao Shuwang
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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