Results 61 to 70 of about 28,076,424 (255)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Relation between Social Media Addiction and Academic Achievement among Students of Nursing Technical Institute [PDF]

Helwan International Journal for Nursing Research and Practice
Background: Social media have had a major influence on students’ academic achievement in recent years. The social media creating many opportunities and threats for students in nursing field. Aim: used to assess the relation between social media addiction
lamiaa elkhalek, ghada mourad, nahla abdeltwab   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Investigation of Social Media Addiction, Experiential Avoidance and Social Emotional Learning Skills in High School Students in Terms of Demographic Variables

Sakarya Üniversitesi Eğitim Fakültesi Dergisi
The main purpose of this study was to examine how social media addiction, experiential avoidance, and social emotional learning skills of high school students differed according to some demographic variables. The participants consisted of 721 (439 female,
Gökçen Aydın, Sidar Turan
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Online gaming addiction in children and adolescents: a review of empirical research [PDF]

, 2012
Background and aims: Research suggests that excessive online gaming may lead to symptoms commonly experienced by substance addicts. Since games are particularly appealing to children and adolescents, these individuals may be more at risk than other ...
Kuss, DJ, Griffiths, Mark D., Griffiths, MD, Kuss, Daria J., Daria J. Kuss, Mark D. Griffiths   +5 more
core   +1 more source

The Influence of Internalizing Problems on Social Media Addiction in Young Adults: An Empirical Study

Maskana
As social media use continues to expand, its potential effects on mental health have become a growing concern, especially for young adults who are among the most active users.
Iason Psiachos, Miguel Ángel Carrasco Carrasco, Pablo Holgado-Tello   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A Study on Health Nutrition Obsession, Social– Physique Anxiety, and Social Media Addiction of Young Individuals

The objective of this research is to explore the connections between preoccupation with healthy dietary habits, social physical apprehension, and addiction to social networking platforms among young people.
Merve Kişi, Selin Kalender
core   +1 more source